Autoimmune Disease Adverse Events immediately post Vaccination

Early addition of new article

My article on immediate onset autoimmune disease adverse events with immediate onset following vaccinations has been peer-reviewed and accepted. It is currently being edited and typesetting errors are being corrected. The early version before corrections is posted online here: Ricke, GTM (2023) https://doi.org/10.36922/gtm.1455

One definition of an autoimmune disease is a condition resulting from an anomalous response of the adaptive immune system attacking part of the body (self). Adaptive immune responses likely response from triggering exposures like pathogen infections, etc. Adaptive immune reponses have time frames ramping up by 7 to 11 days. Rapid triggering of autoimmune diseases seems to be inconsistent this model unless conditions are pre-existing.

The FDA & CDC Vaccine Adverse Event System (VAERS) collects voluntary sumissions of adverse events following vaccinations. Only a small subset of the actual adverse events are reported to VAERS. An estimate of this fraction is termed the under-reporting factor (URF). URF estimates range from 1/20 to 1/30 or 1/40 to 1/50. In the above article, I estimate for the COVID-19 vaccines, the URF might be close to 1/240. This means that as few as 1 adverse event out of every 240 are actually reported to VAERS for the COVID-19 immunizations. This needs to be considered in the context of more adverse events have been reported in VAERS for the COVID-19 vaccines than for all other vaccines combined.

Ricke, GTM (2023) Figure 1. Autoimmune diseases day of onset (1 of 2) (note Y-axis is log(10) scale).

Note that these autoimmune diseases (see also Figure 2 in the article) predominately have immediate onset reports within VAERS!

Normally, autoimmune diseases are thought to be triggered by shared epitope(s) (small segments of proteins recognized by immune responses) between the vaccine protein(s) and human proteins. While this may have happed to create the pre-existing condition, the timeframe for adaptive immune responses are in the 7 to 14 days - not peaking within 24 hours! Very similar patterns are shared by multiple vaccines (five of which are shown in the Figure above). These unrelated vaccines do not share anything in common. But the innate immune responses are shared. In this article, the possibility of pushing individuals with pre-existing conditions over a disease threshold is advanced.

I also note here that Dr. Geoff Pain has pointed out that endotoxin contaminations are an equally probable possibility.

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